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Additional non-oral contraception is advised for 4 weeks after starting treatment and for 4 weeks after each dose increase If pancreatitis is suspected (severe, persistent abdominal pain with or without vomiting), stop Mounjaro immediately and seek urgent medical assessment Mounjaro is not indicated for type 1 diabetes or diabetic ketoacidosis The medication is not recommended during pregnancy or breastfeeding Patients should report any suspected side effects via the MHRA Yellow Card Scheme

I heard someone mention there is some genetic variant which may be at play here

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J Clin Investig 25:495497 Hensley CT, Wasti AT, DeBerardinis RJ (2013) Glutamine and cancer: cell biology, physiology, and clinical opportunities